Scientists Create Human-Sheep Hybrid; Are We Playing God?

Scientists Create Human-Sheep Hybrid; Are We Playing God?

A team of scientists successfully bred the first human-sheep hybrid, developing technology that could expand the availability of organs for transplant procedures. The embryo wasn’t allowed to develop past 28 days, but that hasn’t made this creation of chimeras any less controversial.

Human-Sheep Chimeras

The recent breakthrough is the second of its kind after scientists successfully crossbred human and pig cells last year. They initially chose pigs as an ideal candidate for hybridization due to similarities in organ structure, but their attempts yielded too low of a human cell count to effectively grow compatible organs.

With this latest chimera, scientists have increased the cell count ratio of human to sheep cells to one in ten thousand, a tenfold improvement from the human-pig hybrid. But in order to grow a human organ, the team thinks it would need to improve that ratio to one in a hundred.

 

human sheep hybrid

 

The demand for healthy organs continues to rise globally, with over 115,000 people on a waiting list for a lifesaving organ in the U.S. alone. On average, there are nearly 100 transplants that take place in the U.S. every day.

With the demand for certain organs outpacing supply, some countries have used questionable practices to appease those shortages. The development of hybrids through genome editing and stem cell research has presented a potential opportunity to solve the problem without the need for a human donor. Though it hasn’t been met with universal acceptance.

Scientists use the CRISPR and Cas9 gene editing tools to isolate specific strands of animal DNA and replace them with human DNA, essentially hacking into the evolutionary process. In addition to sheep and pigs, the technology was used to cure disease and implant human brain cells in rodents, inevitably begging the question of whether this could result in humanlike consciousness in animals or any number of other horrifying possibilities one might imagine.

Though the ostensible intentions of these project are benevolent, some feel as if scientists are playing god. It’s not hard to imagine countries with fewer ethical dilemmas acquiring access to the technology and creating deformed creatures with a greater capacity for consciousness.

But scientists working on the project have attempted to assuage those fears, saying their work could save the lives of thousands waiting for a transplant if research is continued further. In many countries, including the U.S. and U.K. there are laws preventing scientists from developing hybrid embryos past a certain stage, though this latest research has started to open up the possibility for approval on a case-by-case basis.



Scientists Just Inserted a Human Intelligence Gene Into Monkeys

Scientists Just Inserted a Human Intelligence Gene Into Monkeys

A team of Chinese scientists recently inserted copies of a human gene believed to be associated with intelligence, into the brains of rhesus monkeys in an attempt to narrow the intellectual evolutionary gap. And according to their results, monkeys who were introduced to MCPH1 showed “remarkable” improvements in short-term memory.

The experiment sparked similar ethical concerns as when a Chinese scientist modified the genes of a human baby late last year, using CRISPR technology to give it HIV immunity.

But despite the dreadful image of an ape with near-human sentience, à la Cornelius from Planet of the Apes, the study arouses some interesting relevance to the ancient astronaut theory that humans may have been seeded by an advanced species from elsewhere in the cosmos.

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