Why would people undertake such a project? Because despite the rigors, you feel so good, during and after. Imagine no flatulence. Not a single belch. No indigestion, period. You start to experience your body with relish, as if it’s a well-oiled machine, which it is. You can practically hear your digestion purr.

But lest you be tempted to do some version of a panchakarma at home, most experts recommend doing your PK at a professional center, especially for the first time. Panchakarma is tuned  individually with constitution and specific disorders in mind. It’s a process that requires close observation and supervision.

When is a good time to do a PK? Often designed to correspond with the change of seasons, according to Ayurveda expert John Douillard, “I always feel the best time to detox or do Panchakarma is when you have the time to really rest and retreat yourself.”

PK is a lot more drastic than a mild cleanse that involves a lot of fresh pressed juices and the occasional sauna. For a PK, you will be asked to drink ghee, submit your tummy to daily kneading (abhyanga), take special herbs to induce vomiting and elimination, and unplug from the world at large (renouncing phones, screens, and even books) to the best of your ability. And the mainstay of your diet will be kitcheree, a perfectly balanced blend of rice and pulses, lightly spiced and cooked to a fragrant mush, designed to be the easiest thing to digest.

In sum, it’s not for the faint of heart, nor the physically weak. And even for those robust enough to take it on, because of its extremity, it needs to be eased into with a pre-PK diet (mainly kitcheree, vegetables and ghee), that primes the body for the detox ahead.

Finally, although panchakarma is often thought of as the entire procedure, it really is only one part of a group of therapies belonging to a whole cohort of cleansing procedures. Pancha means five and refers to five favored purification techniques that take place during the cleanse. Here’s a brief version of what you will encounter on your PK journey:

Vamana

Also known as therapeutic vomiting, vamana is a way to get rid of excess mucous (kapha). According to Vasant Lad, a renown Ayurvedic author and doctor, “this also releases repressed emotions that have been held in the kapha areas of the lungs and stomach along with the accumulated dosha.”

The rewards: A lightness in the chest, unobstructed breathing, clear thinking, clear voice, good appetite.

Virechana

Administered towards the end of your PK, after the doshas have had a chance to soften, the toxins loosened by copious amounts of ingested ghee, and prodigious amounts of oil rubbed into every crevice of your body, the final push so to speak, is virechana (therapeutic laxatives) day. No breakfast is eaten that day and a bitter tasting laxative is mixed with juice in an attempt to mask its taste. The laxative, which induces bowel movements cleanses the body of excess pitta accumulation, purifying blood and clearing toxins. The laxative targets the toxins accumulated in the liver and gallbladder, thus completely cleansing the gastrointestinal tract.

The rewards: Virechana is like a weapon of mass destruction for any lingering accumulated toxins. It gets at the motherlode of bile—excess pitta—that makes its home in the small intestine. After virechana, the overall effect is one of lightness, clarity, and strength.

Basti

Therapeutic enemas, made from sesame oil and herbal blends, are administered during a PK, or self-administered afterwards, at home. The idea of basti is that it gets at the root of vata related diseases, such as constipation, distention, chronic fever, cold, sexual disorders, kidney stones, heart pain, backache, sciatica and other pains in the joints. Vata is thought to reside in the bone tissue, therefore the enema delivery system means  that treatment goes into the deeper tissues, like the bones, and corrects vata disorders.

The rewards: Basti can be used for a variety of reasons, including bowel regularity, joint support, excess vata causing gas, nervous system support, and healthy sleep patterns. Basti promotes overall vitality, which begins with a healthy and supple colon that in turn sets the foundation for well-being, a graceful aging process, luster and a healthy glow.

Nasya

Not applicable for everyone, nasya is a nasal therapy (massaging the inner walls of the nose with ghee) that is indicated for prana disorders, sinus congestion, migraine headaches, convulsions and certain eye and ear problems.

The rewards:A clear respiratory tract, plus a major side benefit: It is believed in Ayurveda that the nose is the pathway to the brain. Nasya is thought to improve intelligence and memory.

Rakta Moksha

Therapeutic bloodletting is not allowed in U.S. PK clinics due to obvious liabilities. But in India such treatments do exist, with the purpose of curing many blood-borne disorders.

The rewards: It is good for patients suffering from chronic skin conditions such as psoriasis, vitiligo and eczema, non-healing ulcers, and varicose veins.