Study Shows That Fasting for 3 Days Can Reset The Immune System

Alarm clock,empty plate and utensils on a wooden background

Want to kick that cold or boost your immune system so you don’t even catch that cold in the first place? Forget the copious amounts of Vitamin C or drastic lifestyle changes; it turns out the old adage of starving a cold may actually be scientifically sound advice. That’s according to a study that says two to four days of fasting resets immune systems, benefitting everyone from healthy adults to chemotherapy patients.

How Fasting Helps the Immune System

According to a study in Cell, testing in both mice and humans showed that extended periods of fasting lowered white blood cell counts considerably. This produces a change of the signaling pathways of HSCs or hematopoietic stem cells, which give rise to new blood and immune systems.

One of the study’s authors, Vlater Longo said, “When you starve, the system tries to save energy, and one of the things it can do to save energy is to recycle a lot of the immune cells that are not needed, especially those that may be damaged.”

This can be especially beneficial for the elderly and those with autoimmune disorders who are more susceptible to disease and illness. Another find from the study showed that fasting lowers levels of a growth hormone known as IGF-1, which is linked to cancer, aging and tumor growth.

Scientists are also seeing the benefits of fasting in other areas of health, especially in the field of neuroscience. In one study, they found that fasting twice a week can reduce the risk of Alzheimer’s and Parkinson’s disease. It also found that fasting can challenge the brain in the short term and stimulate two messaging chemicals that are key to the growth of new brain cells. This helps the brain become resistant to protein plaques that lead to neurodegenerative diseases.

A number of Silicon Valley execs are experimenting with fasting as a biohacking technique. Some of these biohackers abstain from food consumption for up to four days, while only drinking water, coffee or tea. CEOs, like Phil Libin, say it puts him in a better mood, keeps him more focused, and even provides a mild euphoria.

The science behind this is similar to the concepts of ketogenic diets where the body, when starved of carbohydrates and glucose, goes into ketosis, producing ketones from the breakdown of fat in the liver. The body uses these ketones in place of glucose, while burning fat to create said ketones.

Benefits of Fasting for Chemotherapy Patients 

In a previous study, Longo and his team found that fasting in animals effectively treats a majority of cancer types. He also found that fasting in addition to chemotherapy is much more effective than chemotherapy alone.

 

3-day-fast-immune-system

 

For cancer patients, chemotherapy can devastate the immune system, which is why chemotherapy is typically supplemented with medicine to boost immune cells. After chemo has ended, it can take nearly a month for the immune system to recover.

Fasting, however, flips a “regenerative switch,” signaling stem cells to create new white blood cells, eventually regenerating the entire immune system. At the same time, the old, inefficient parts of the immune system are disposed of. This process not only reboots the immune system, but it reduces damage done by free radicals and inflammation in the body.

Of course, the study says that patients should consult their doctors to see if their bodies are healthy enough for fasting, as it is not always the right path depending on one’s weight and specific conditions.

Ancient Fasting to Regenerate the Immune System

Fasting has been a tradition practiced by a number of different cultures and religions for hundreds of years.

The ancient Egyptians fasted and purged on a monthly basis in order to cleanse their bodies, believing that all illness emanated from the food they put in their system. When the ancient Greek philosopher, Herodotus, wrote of the Egyptians, he described them as the healthiest of men.

Whether it was Herodotus’ perception or otherwise, many other famous Greek men employed or at least extolled the power of fasting in their lifestyles, including Plato, Hippocrates and Plutarch. The latter was famously quoted as saying, “Instead of using medicine, better fast today.”

Many religions incorporate fasting into their traditions, often under the premise that it brings one closer to god and that it has a purification aspect. In Islam, Ramadan calls for an entire month of fasting, and the Prophet Muhammad encouraged fasting twice a week. In Judaism, there is Yom Kippur and in Christianity giving up a food for Lent is symbolic of Jesus fasting for 40 days in the desert.

With modern medicine, we have become so consumed with the idea of taking a pill for every ailment, when often the solution can be found in our own ability for self-healing.



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How to Live Longer -- Secrets of the Blue Zones

Eating well and exercising are obvious necessities for maximizing one’s lifespan, but many believe that genetics are actually the biggest determinant. But according to the Danish twin study, only 20 percent of longevity is due to hereditary causes. Based on this knowledge, Dan Buettner decided to figure out what it was exactly that contributed to a longer, healthier lifetime. He found there are “Blue Zones,” or areas throughout the world with high concentrations of healthy people living longer than most, due to specific lifestyle and environmental factors.

Where Are the Blue Zones?

Based on demographic research of global populations, Buettner identified five disparate regions having concentrations with health statistics that defied national or world averages. Things like lower rates of cardiovascular disease and cancer were defining factors, as well as abnormally high concentrations of centenarians – people who have lived past the age of 100.

Upon this realization, Buettner published his findings in National Geographic, and subsequently developed a set of guidelines emulating the intrinsic elements of these blue zone lifestyles, that could be applied to anyone.

In the United States, the average life expectancy is just over 78 years for the general population. Women have a higher expectancy than men by almost five years, which is pretty common across most cultures, but in certain “blue zones” life expectancy is significantly higher for both sexes, with residents consistently living into their 90s and beyond.

 

Cool elder lady making rock on sign

 

Sardinia, Italy is home to a region that, at the time of Buettner’s study, boasted the highest concentration of male centenarians in the world. Though mostly concentrated in one area of the island, the statistic was most prominent in a village called Seulo, part of a small mountainous region that was home to 20 blue zone centenarians from 1996-2016. But Seulo has barely maintained its top rank, often trading the title with Okinawa, Japan and the Nicoya Peninsula of Costa Rica.

Buettner visited these regions and studied the lifestyle habits of its denizens. In Sardinia, he noticed that the community was still living a Bronze Age lifestyle, where labor was intertwined with daily life and old age was celebrated.

One of the oldest men in the village was 104 years old and still able to beat Buettner in an arm-wrestling match. The man would wake up at 9 a.m., chop wood, drink a glass of wine, and give advice to a line of townspeople throughout the day, waiting for his wisdom.

This sense of community, regular, but moderate alcohol consumption, and physical activity were three important factors contributing to the Sardinians’ longevity. Their diet included high levels of Omega-3 fatty acids, vegetables, legumes and whole wheat, unleavened bread, and the wine they drank had three times the normal levels of polyphenols, their secret eau de vie.

 

The Blue Zones Longevity

The blue zone diet that was so beneficial to the Sardinians is a common theme across analogous communities. In the U.S., there is a blue zone just outside of Los Angeles in an area called Loma Linda. The town is home to a group of 7th Day Adventists, a conservative group of Christian Methodists. This community ascribes to a diet mentioned in the Bible that recommends eating mostly legumes, seeds, and green plants.

 

blue zones longevity

 

This is the foundation of the blue zone diet, a relative commonality between all of the communities Buettner studied. He found these people eat nutritious food at least 80 percent of the time, and they also make it a point not to overeat. In Okinawa there is a ritual prayer to remind themselves of this, recited before every meal. This anti-overindulgence mantra has been performed for 3,000 years since it was first uttered by Confucius.

Another secret to longevity that Buettner identified was that all of these communities had some sort of involvement in their community and participated in some type of sacred practice.

Whether it was religion or spirituality, these practices of faith typically lead to communal activity and a time set aside for a reprieve from life’s stresses. In Loma Linda the Christian community would celebrate their Sabbath from sunset on Friday to sunset on Saturday, allowing for a full 24 hours of what they referred to as a “sanctuary in time.”

Buettner said this slowing down, or taking time to downshift from life’s daily bustle, reduces an inflammatory response that our bodies kick into gear when we put stress on them. That inflammation has been linked to diseases like Alzheimer’s and heart disease, so when we regularly take action to reduce or eliminate that response, the results are overwhelmingly beneficial.

In Japan, friend groups were designated for an entire lifetime with groups of blue zone centenarians who got together regularly since their youth. These groups also helped in the anti-inflammatory unwinding process, while also providing a social outlet. They call these associations “Moais” which provide not just camaraderie, but support for times when they feel down or have something big going on in their lives.

 

Secrets of the blue zones venn diagram

 

 

Buettner recognized this across all of the blue zones and said that he believed this was the primary factor for achieving longevity, the foundation upon which every other lifestyle choice was built.

And nearly tantamount in its efficacy for a long, healthy life, he identified what the Okinawans call “Ikigai,” and the Costa Ricans call a “plan de vida” –  a lifelong purpose. He found that devoting oneself to a passion or duty, not only provides a sense of direction and pride, but keeps your mind active and functioning.

You don’t have to move to these blue zones to dip into their fountain of youth tactics when Buettner has done the hard work of uncovering their secrets. By implementing some of these conscious lifestyle choices you too can reduce your risk of disease, live a healthier life, and maybe last long enough to join the centenarian club.

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