Study Shows Microdosing Psilocybin Boosts Mood, Mental Health
A new study provides the most compelling evidence to date on the impressive mental health benefits of microdosing psilocybin.
While there has been an ever-increasing number of studies showing the efficacy of treatment of mental health disorders with psychedelics, there has been relatively little research on the practice of microdosing.
Microdosing, or repeatedly taking small, barely perceptible amounts of psychedelics, has been exponentially increasing in popularity, with a wide range of people reporting a multitude of improvements to their psychological wellbeing.
The latest scientific study to look at the effects of microdosing was conducted by researchers at the University of British Columbia, as well as other leaders in the fields of psychology and mycology. The study followed 953 people who used small, repeated doses of psilocybin for about 30 days, as well as a control group who did not microdose.
While the exact dosages of psylocibin that participants self-administered varied somewhat, they were all low enough to not impact daily functioning.
Over a one-month period, participants took these psylocibin microdoses three to five times per week and were asked to complete a number of assessments through a smartphone app that tracked their mental health symptoms, mood, and measures of cognition. The findings definitively showed that the microdosing participants demonstrated greater improvements in mood and mental health than those in the non-microdosing control group.
Study author Dr. Zach Walsh, told news nine, “Our findings of improved mood and reduced symptoms of depression, anxiety, and stress add to the growing conversation about the therapeutic potential of microdosing.”
In addition, as researchers were looking to assess cognitive benefits, participants used a finger tap test to measure their psychomotor ability, which is a marker for neurodegenerative disorders such as Parkinson’s Disease. The findings showed improvement in these abilities, especially in those over the age of 55.
Another fascinating component of this study was the investigation of the use of stacking — where psilocybin mushrooms are combined with other non-psychedelic substances such as lion’s mane mushrooms. The study noted that those who stacked had greater improvements than those who did not. Researchers are very enthusiastic about the results and adamant about the need for further research in the form of more rigorous placebo-controlled studies.
As Dr. Walsh stated to the Vancouver Sun, “We have an epidemic of mental health problems, with existing treatments that don’t work for everyone. We need to follow the lead of patients who are taking these initiatives to improve their well-being and reduce suffering.”
New Gene Discovery May Explain Rapid Human Brain Evolution
A revealing new study on human evolution and brain development has just been published. Could this lend credence to the stoned ape theory of brain evolution?
About 300,000-800,000 years ago the human brain experienced a massive and accelerated growth spurt. Scientists have offered many explanations for how and why this may have occurred, but a new study out of Boston Children’s Hospital focused on a fast-evolving set of the human genome called human accelerated regions (HARS). Previous studies have found about 3,100 HARS during brain development, but the team at Children’s Hospital determined one HAR gene PPP1R17 could be responsible for or play a significant role in, rapid brain development. Further, they discovered this works differently in humans than in other animals.
Ben Stewart, the host of Gaia’s Limitless series, said,”[T]hese regions of the human DNA may hold some kind of an answer at the rapid explosion of human neo-cortex because if you think of it evolutionarily, there’s not been one creature, at least on planet Earth, that has been studied that had any organ increase in size as large and as rapidly as the human brain did, so there’s definitely some unanswered questions there.”
“I’m pretty sure that these HARS regions are being looked at for something very unique in the evolution of the brain, and my own personal twist on it is this also might be important when we start looking at brian-machine interfaces and how the brain can potentially cause mutations to adapt to some kind of technology in the brain to enhance or evolve the human brain,” Stewart said.
How could this new discovery be related to the Stoned Ape theory?
“There’s a possibility that the Stoned Ape theory could lead into this. Now, the Stoned Ape theory was really popularized by Terence McKenna,” Stewart said. “Over time, you would have some of our ancient ancestors, hominids, that would be following behind bovine creatures, cows, and in the cow patties in the fields that would naturally, having followed these creatures around for hundreds of thousands of years or whatever it might have been, that they would have started eating the mushrooms, the psilocybin mushrooms that grow naturally in cow patties. These experiences tickling the language centers and other parts of the brain, bringing down the rigidity of the default mode network, and activating other communication hubs within the brain, that could actually explain the rapid explosion of the human neocortex.”
“In this article, they’re saying that these human accelerated regions act differently in humans than they do in primates or creatures like mice and ferrets that they’ve looked into now. So, potentially if there is some connection with the Stoned Ape theory, that psychedelics or psychotropics helped in the expansion of the human neocortex, and made us as, at least psychologically, so much different than the rest of the creatures on Earth, then there may be something to look at here.”
