Study Shows Microdosing Psilocybin Boosts Mood, Mental Health
A new study provides the most compelling evidence to date on the impressive mental health benefits of microdosing psilocybin.
While there has been an ever-increasing number of studies showing the efficacy of treatment of mental health disorders with psychedelics, there has been relatively little research on the practice of microdosing.
Microdosing, or repeatedly taking small, barely perceptible amounts of psychedelics, has been exponentially increasing in popularity, with a wide range of people reporting a multitude of improvements to their psychological wellbeing.
The latest scientific study to look at the effects of microdosing was conducted by researchers at the University of British Columbia, as well as other leaders in the fields of psychology and mycology. The study followed 953 people who used small, repeated doses of psilocybin for about 30 days, as well as a control group who did not microdose.
While the exact dosages of psylocibin that participants self-administered varied somewhat, they were all low enough to not impact daily functioning.
Over a one-month period, participants took these psylocibin microdoses three to five times per week and were asked to complete a number of assessments through a smartphone app that tracked their mental health symptoms, mood, and measures of cognition. The findings definitively showed that the microdosing participants demonstrated greater improvements in mood and mental health than those in the non-microdosing control group.
Study author Dr. Zach Walsh, told news nine, “Our findings of improved mood and reduced symptoms of depression, anxiety, and stress add to the growing conversation about the therapeutic potential of microdosing.”
In addition, as researchers were looking to assess cognitive benefits, participants used a finger tap test to measure their psychomotor ability, which is a marker for neurodegenerative disorders such as Parkinson’s Disease. The findings showed improvement in these abilities, especially in those over the age of 55.
Another fascinating component of this study was the investigation of the use of stacking — where psilocybin mushrooms are combined with other non-psychedelic substances such as lion’s mane mushrooms. The study noted that those who stacked had greater improvements than those who did not. Researchers are very enthusiastic about the results and adamant about the need for further research in the form of more rigorous placebo-controlled studies.
As Dr. Walsh stated to the Vancouver Sun, “We have an epidemic of mental health problems, with existing treatments that don’t work for everyone. We need to follow the lead of patients who are taking these initiatives to improve their well-being and reduce suffering.”
Study Shows Psilocybin Promotes New Growth of Neurons in Brain
A major development in the treatment of depression shows psilocybin can actually grow connections inside the brain without a hallucinogenic trip.
As we have previously reported, researchers have found that psilocybin, the active ingredient in psychedelic mushrooms can reduce major depressive disorder in humans. but we have not known how it works or how long it will last.
Now a new study out of Yale University shows one dose of psilocybin in mice creates rapid and sustained connections between neurons.
Steven Grant Ph.D. Director of Research at the Heffter Research Institute, a non-profit organization a non-profit organization that promotes research into hallucinogens and the brain, has studied how drugs affect the brain for nearly 50 years.
“So, what they discovered, not only does a single dose of psilocybin produce the formation of neuronal growth as measured by what are called ‘spines,'” Grant said. “Spines are the little nubby protrusions off the branches of a neuron that are associated with the connections with other neurons, so presumably the more spines the more connections you have. And the study found that psilocybin not only produced growth in the number of spines, but it persisted over a month. So that’s remarkable — one dose produces this long-lasting change in the ability of the neurons to form new connections.”
