Scientists Find Breakthrough Use of Light to Kill Cancer Cells
In a world-first, scientists have developed a breakthrough treatment that uses light to kill cancer cells.
We often think of light as a life-giving source, but in the case of photoimmunotherapy — the use of light to help a person’s own immune system fight cancer — light can both be a source of life, for the patient, and death, to cancer cells.
A multidisciplinary team of European scientists joined forces to design the new treatment, which works by combining a special fluorescent dye with a cancer-targeting compound.
Shining light on the compound forces cancer cells to glow in the dark, helping surgeons to remove more of the tumors compared with existing techniques.
Then, the surgeon would shine near-infrared light on the site, switching the compound into tumor-killing mode and killing off any remaining cells.
The trial of this therapy was done on mice with a particularly aggressive form of brain cancer called glioblastoma.
Findings showed that the mice had clear signs of tumor death in as little as one hour after exposure to the light. The treatment also triggered an immune response that could mount a new attack on cancer should it come back.
Study leader Dr. Gabriella Kramer-Marek told The Guardian, “Brain cancers like glioblastoma can be hard to treat, and sadly, there are too few treatment options for patients. Surgery is challenging due to the location of the tumors, and so new ways to see tumor cells to be removed during surgery and to treat residual cancer cells that remain afterward could be of great benefit.”
Scientists are quite hopeful that the results will be duplicated when they study the treatment of humans. In the meantime, this trial has shined a light at the end of a long, dark tunnel.
Scientists Finally Finished Mapping the Human Genome
Scientists announce they have finally completed the map of the entire human genome. Will the information contained within unlock our true potential for health and wellbeing, or is there another more expansive perspective on the role genes play in our lives?
After decades of research, scientists have recently announced the completion of the human genome, what some call “the genetic instruction book.” Widely used for guiding biomedical research, many experts herald this as a crowning achievement in the field.
Dr. Bruce Lipton is a cellular biologist and a pioneer in the field of epigenetics, which takes a comprehensive, cutting-edge approach to the understanding of our relationship to our genes.
“Most people are really excited about the fact that the human genome has been deciphered; they’ve identified how many genes are in the human genome,” Lipton said. “The original reason for the human genome was, it was thought the genes control all the characteristics of our life and therefore if I had a compendium of all the genes I could fix anybody who has a characteristic they want to change. Francis Crick, one of the cofounders of the story, came up with something called “the central dogma,” the belief that genes are the source of biological information.
“They’re translated into another form of nucleic acid called RNA. So, DNA goes into RNA which is like a xeroxed copy of the DNA, and then the RNA is used as a template to make the proteins of the body,” he said. “According to the central dogma, information only flows in one way — it flows from the DNA to the RNA to the protein. This led to an understanding called ‘genetic determinism.’ Genetic determinism is the belief that the genetic blueprint of your life is carried by the DNA that you inherited at the moment of conception.”
