Doctors Discover New Organ in Human Body To Help Treat Cancer
Scientists discovered a new organ in the body that turns out to be one of the largest. The interstitium is a series of fluid-filled compartments found beneath the skin, and could hold the key to understanding the spread of one of humanity’s biggest medical dilemmas: cancer.
Originally perceived as connective tissue, the interstitium has eluded doctors and biologists as an organ of its own, with a specific task of transporting and filtering fluids throughout the body.
Before this discovery, it was assumed that our skin was the largest organ, but now the interstitium may prove to be even larger. This new distinction would mark the body’s 80th organ.
The word interstitium derives from the Latin “inter,” meaning between, and “sistere,” meaning to place, –  the place between. Doctors believe this in between organ may also act as a sort of cushioning to keep our organs safe.
The interstitium is the source of lymph, where white blood cells are transmitted to fight infections. It is also important for transporting protein from the blood to a multitude of organs and cells.
Researchers still need to confirm whether it qualifies as an organ, but a new perception of the interstitium seems promising for tracking and advancing the spread of diseases. While the tissue is important for transporting fluids throughout the body, it is also likely to be responsible for spreading cancer.
The organ was originally looked over because of its pervasiveness and the way it was studied. In the past, doctors sliced into the interstitium during biopsies, upon which all of its fluid would drain, leaving it flat and solid.
But now through an endoscopy procedure, in which doctors examine organs using a tiny camera attached to a thin, flexible tube, they gained a new perspective on the interstitium and the important role it plays in supporting bodily functions.
The paper published in the journal Nature says the existence of the location and structure of larger inter- and intra-tissue spaces is described vaguely in literature and that in vivo advances in microscopy were responsible for better understanding it. These advances will likely lead to further discoveries in the future, while also showing just how much we still have to learn about our own anatomy.
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New Study Looks at Ancestor's Gut Microbiome to Improve Health
A fascinating new study shows our gut microbiome has been experiencing a potentially catastrophic loss of diversity over the last millennium, possibly giving rise to various common chronic diseases. Is it too late to avoid irreversible damage to our health?
While most of us don’t ever think about it, we coexist with over 100 trillion microbes, the majority of which live in our gut and are essential to our health. Though the existence of the microbiome was first recognized in the 1990s, the full understanding of its importance and mechanisms is still in its infancy.
Dr. Alex Kostic is a microbiologist at Harvard Medical School, who has been studying the microbiome as a mediator of disease. “You know, this concept of the microbiome as a community of organisms living on humans and other mammals, and playing an integral role in our physiology really is a new concept, something that people have only been studying for the past 10-15 years or so,” Kostic said. “But what we’ve come to realize, as we study the ecology of all of the microorganisms living on humans, especially in the gut, is that it’s incredibly diverse, and pathogens are really the exception to the rule. Everything else has a lot of other roles that we’re still trying to tap into, but we can be fairly confident that they’re not driving disease in people.”
In their quest for a clear picture of the microbiome, researchers have recently turned to studying its history.
“What’s really gotten me interested in the history of the human microbiome, is this concept of being able to identify, if it exists, a ‘universal ancestral human microbiome,’ something that was common to all of us before the process of industrialization,” Kostic said.
