New Study Looks at Ancestor’s Gut Microbiome to Improve Health
A fascinating new study shows our gut microbiome has been experiencing a potentially catastrophic loss of diversity over the last millennium, possibly giving rise to various common chronic diseases. Is it too late to avoid irreversible damage to our health?
While most of us don’t ever think about it, we coexist with over 100 trillion microbes, the majority of which live in our gut and are essential to our health. Though the existence of the microbiome was first recognized in the 1990s, the full understanding of its importance and mechanisms is still in its infancy.
Dr. Alex Kostic is a microbiologist at Harvard Medical School, who has been studying the microbiome as a mediator of disease. “You know, this concept of the microbiome as a community of organisms living on humans and other mammals, and playing an integral role in our physiology really is a new concept, something that people have only been studying for the past 10-15 years or so,” Kostic said. “But what we’ve come to realize, as we study the ecology of all of the microorganisms living on humans, especially in the gut, is that it’s incredibly diverse, and pathogens are really the exception to the rule. Everything else has a lot of other roles that we’re still trying to tap into, but we can be fairly confident that they’re not driving disease in people.”
In their quest for a clear picture of the microbiome, researchers have recently turned to studying its history.
“What’s really gotten me interested in the history of the human microbiome, is this concept of being able to identify, if it exists, a ‘universal ancestral human microbiome,’ something that was common to all of us before the process of industrialization,” Kostic said.
Watch more:
About the Author
Water-Only Fasting Protocols Found to Enhance Cancer Treatments
Intermittent fasting has become popular for health and weight loss. But could fasting also be a highly effective tool for fighting and reversing cancer?
Across the world, nearly every culture has a tradition of fasting, but in our modern lives we’ve created a world of surplus and with it a constant and easily satiated hunger. With this excess food, our society has become plagued by diseases of excess.
Dr. Alan Goldhamer is the founder of True North Health Foundation, a therapeutic clinic for water-only fasting that helps patients suffering from a range of illnesses including hypertension, inflammation, autoimmune disorders, and cancer.
“We’ve gone from being criminal quacks to cutting-edge researchers because this idea of fasting has definitely gained some popular support,” Goldhamer said. “Our approach is very different, we believe that there is a cause of real health and the cause of health is healthful living. So, we focus on diet, sleep, (and) exercise, and we use fasting to undo the consequences of dietary excess, essentially. That’s why the conditions that respond the best to fasting are the conditions caused by dietary excess – so, obesity, high blood pressure, cardiovascular disease, Type II diabetes, autoimmune diseases, and certain forms of cancer, including Lymphoma.Â
Studies have shown that fasting acts to help the body’s natural ability to destroy dead or diseased cells — a process called autophagy. Now, doctors have begun to study how fasting protocols in conjunction with drugs, such as chemotherapy, can improve the efficacy of cancer treatment.
“It turns out autophagy is the process the body uses to get rid of cellular debris — aging cells and cancer cells — and it turns out that fasting is one of those things that may profoundly enhance autophagy in, not just humans, but also in other animals. In fact in rats, if you do periodic fasting with rats you can double their lifespan (everything else being equal). So, this is something that’s very interesting and promising. I don’t know that we have what I would consider definitive research on the issue, but it certainly raises one of the mechanisms by which fasting may also be effective,” Goldhamer said.
