Jo Cameron’s Life Without Pain; A Story of Rare Genetic Mutations
When Jo Cameron underwent a double hand surgery procedure, which would have left most people in excruciating pain, she left the hospital happy, vivacious, and in no pain whatsoever. At the time, Cameron was 65 years old and should have been even more susceptible to the surgery’s painful aftermath. Recognizing this anomalous behavior, doctors decided to investigate and found Cameron’s DNA contained two genetic mutations that made her unable to feel pain either physically or emotionally.
A Happy Genetic Mutation
Like anyone else, Cameron has been scraped, burned, and bruised throughout her life. But these physical injuries had little effect on her. After two surgeries, which left doctors baffled by her recovery — she needed only two aspirin the day after a hip-replacement surgery to deal with the pain — she was referred to a team of specialists at University College London’s Molecular Nociception Group (UCL).
Following a thorough DNA study, scientists at UCL published an unusual case report in the British Journal of Anaesthesia, revealing their findings of two genetic mutations:
Genetic Mutation #1:
This mutation affects the FAAH gene, which produces the enzyme responsible for breaking down anandamide — a neurotransmitter that’s been dubbed “the bliss molecule” (appropriately named after the Sanskrit word for bliss, "ananda") for its ability to bind to THC receptors, affecting mood, appetite, pain, and memory. When the FAAH genes break down anandamide, we experience physical and mental pain. But with a mutation like Cameron’s, the bliss molecule is allowed to preside, bringing out anandamide’s positive effects.
Surprisingly, this genetic mutation is not as uncommon as one may think, as about 20 percent of Americans are said to possess it. However, this percent of the populace doesn’t have Cameron’s second mutation, which compounds the effect and prevents her from experiencing any pain at all.
Genetic Mutation #2:
The discovery of this rare genetic mutation, named the FAAH-OUT gene, was said to be scientifically groundbreaking, as it was found to be a previously unidentified gene. As may be guessed from its name, the FAAH-OUT gene has a bearing on the FAAH gene, essentially turning down its activity. Working in concert, these two genetic mutations enabled Cameron to live her life unable to feel pain.
“I knew that I was happy-go-lucky, but it didn’t dawn on me that I was different. I thought it was just me. I didn’t know anything strange was going on until I was 65,” she told the The Guardian,
Development of New Pain-Relief Treatments
The search for reliable pain-relief treatments has been ongoing for millennia, with doctors and researchers historically relying on medications that target opioid receptors. But of course, this approach has led to an epidemic of addiction, abuse, and fatality, with more than 130 people now dying in the United States from opioid addiction daily.
Cameron’s genetic mutations bring the FAAH and FAAH-OUT genes into the spotlight, when it comes to pain-relief alternatives. While experimental drugs involving FAAH receptors previously failed, the FAAH-OUT discovery provides researchers more insight on how to target the endocannabinoid pathway involved in a variety of physiological and cognitive processes, including pain sensation.
To many sufferers who have turned to medical marijuana for relief, it is no surprise that working with endocannabinoid receptors should be considered a safe and successful means of ameliorating chronic pain. For years, individuals reeling from a range of maladies — from cancer to Crohn’s Disease to paralytic anxiety to suicidal depression — have fought to legalize marijuana as a powerful treatment option.
Is Being Unable to Feel Pain Necessarily Good?
While the prospect of dulling or totally eradicating pain may be alluring, it is important to bear in mind why all living beings experience pain in the first place: as a survival mechanism.
Pain is the catalyst for both physical and emotional lessons.
Experiencing physical pain alerts us to something being physiologically wrong. Just because one doesn’t have pain doesn’t mean he or she is immune to illness or injury. For example, if one sustains a wound and isn’t aware of it, left untreated, that wound could become infected and lead to something more serious like illness or even death; pain can be a biological warning pointing to a larger problem.
The same holds true for emotional pain. Serving as another survival mechanism, emotional pain generally runs along the spectrum of fear and happiness. Being highly in-tune with emotional well-being often results in increased self-awareness and when the balance shifts toward pain one is instinctually alerted to danger. Juxtaposed against agony or discomfort, a feeling of well-being also tends to foster a sense of safety. Â
The case of Cameron, who only realizes she’s burning herself on the oven when she smells singed flesh, but feels no pain to warn her, prompts a great philosophical question: What is life without pain?
Although pain can be regarded as a purely biological function, its absence seems to thwart the natural laws of the yin and yang. Can one truly know the height of happiness if he or she hasn’t known the depths of sorrow? While some may envy or dream of life without pain, it may be argued that everything in life is relative, which gives pain a rarely-appreciated purpose.
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Check out Alan Watts’ explanation of the Zen Buddhist perspective of pain:
Tapping Or EFT: What It Is And How It Can Help You Emotionally
Tapping, also known as EFT (Emotional Freedom Technique), is a therapeutic tool that seeks to release emotional blocks through the stimulation of energy points on the body. This technique combines elements of psychology and acupressure to address stress, anxiety, pain, and other difficult emotions. In this article, we explore what tapping is, how it works, and how it can help you regain your emotional well-being.
Table of Contents
- What Is Tapping And How Does It Work On Your Emotions?
- How Does Tapping Work On The Body And Mind?
- Benefits Of Tapping: What This Tool Is Good For
- How To Practice A Tapping Round Step By Step
- What Does Science Say About Tapping?
- What Is The Origin Of Tapping And Who Developed It?
- How To Begin Incorporating Tapping Into Your Daily Life
What Is Tapping And How Does It Work On Your Emotions?
Tapping is an emotional self-regulation technique that consists of gently tapping with the fingers on certain points of the body linked to the meridians of traditional Chinese medicine. While stimulating these points, phrases are spoken aloud that acknowledge the emotional issue being addressed. This combination allows the release of energetic blocks associated with memories, thoughts, or sensations that cause distress.
On an emotional level, tapping helps to process difficult experiences without repressing them or becoming trapped in them. By validating what we feel while simultaneously activating specific points on the body, a sense of relief and inner safety is created. That’s why it is considered an effective tool for calming states of anxiety, stress, fear, guilt, or sadness.
How Does Tapping Work On The Body And Mind?
From a physiological perspective, tapping reduces the activation of the sympathetic nervous system, which is responsible for the fight-or-flight response to stress. By stimulating certain acupuncture points, calming signals are sent to the brain, which can lower cortisol levels and promote a state of relaxation. This allows the body to feel safer, even when facing difficult emotions or memories.
On a mental level, tapping supports the reorganization of beliefs associated with negative emotions. By repeating conscious phrases during the process, patterns of thought that often operate automatically are reprogrammed. The result is a deeper connection with what we feel, accompanied by an internal sense of relief, stability, and perspective.

Benefits Of Tapping: What This Tool Is Good For
Tapping is a versatile technique that can be used to relieve emotional, physical, and energetic discomfort. By focusing on the connection between body and emotion, it allows the release of internal blocks and the restoration of balance.
- Stress reduction: Helps calm the nervous system and relieve accumulated tension. It’s useful during times of emotional or mental overload.
- Anxiety management: Allows the identification of thoughts that fuel anxiety and the release of the associated emotional burden. Improves the sense of internal control.
- Fear processing: Facilitates facing fears and phobias with greater stability. Reduces automatic reactions to stimuli that previously triggered alarm.
- Releasing repressed emotions: Offers a safe space to recognize and express what we feel. Encourages emotional flow without judgment.
- Improving insomnia: By reducing anxiety and mental noise, it supports deeper rest. It can also be used before bed as a relaxing routine.
- Support in physical pain: Relieves bodily tension related to unexpressed emotions. Complements physical treatments from a holistic perspective.
- Support during personal processes: It’s helpful during times of change, grief, or personal growth. Aids in integrating emotions and finding inner clarity.
How To Practice A Tapping Round Step By Step
Practicing a round of tapping is simple and does not require external tools. All you need is a quiet space, your hands, and the willingness to connect with what you’re feeling. Below we share the essential steps to perform a tapping round:
- Identify and name what you’re feeling: The first step is to connect with a specific emotion, recurring thought, or physical discomfort you want to address. The more specific the identification, the more effective the practice.
- Formulate a setup phrase: This phrase should include the problem you’re feeling and a statement of acceptance. An example could be: “Even though I feel afraid of change, I deeply and completely accept myself.” Repeat this phrase while stimulating the first point.
- Stimulate the karate point: With the fingers of one hand, gently tap the outer edge of the other hand (known as the karate point). While doing this, repeat the setup phrase out loud or mentally about three times.
- Tap through the body points: Then proceed with the traditional tapping sequence: eyebrow, side of the eye, under the eye, under the nose, chin, collarbone, and under the arm. At each point, apply light taps while naming what you’re feeling or repeating phrases related to the issue being worked on.
- Observe and close: At the end of the round, take a deep breath and assess whether the intensity of the emotion has changed. You can repeat the process if needed or close with a positive phrase that affirms the new emotional state, such as: “Now I feel calmer and more at peace.”

What Does Science Say About Tapping?
In recent years, tapping has attracted the interest of the scientific community, especially in the fields of clinical psychology and mind-body medicine. Various studies have indicated that the practice of EFT can significantly reduce cortisol levels, the stress hormone, and improve symptoms associated with anxiety, depression, and emotional trauma.
Although it is still considered a complementary therapy, institutions such as the APA (American Psychological Association) have begun to recognize its therapeutic potential, particularly when it is integrated with other approaches. Research continues to expand, but early results suggest that tapping is not only safe, but also effective in promoting emotional well-being and reducing nervous system activation.
What Is The Origin Of Tapping And Who Developed It?
Tapping was developed in the 1990s by Gary Craig, an American engineer with training in neuro-linguistic programming (NLP). Craig was inspired by the work of psychologist Roger Callahan, who had created a technique called TFT (Thought Field Therapy) that combined acupressure and verbal therapy. By simplifying that method, Craig designed what we now know as EFT (Emotional Freedom Technique).
The foundation of tapping is found in traditional Chinese medicine, particularly in the stimulation of the body’s energy meridians. Craig proposed that by applying gentle tapping on specific points while working on a concrete emotion, it is possible to unblock stagnant energy and restore internal balance.
Since its creation, tapping has spread widely as an emotional self-regulation technique that is accessible, practical, and adaptable to different contexts. Its popularity grew due to its ease of use and the testimonials of people who report significant relief with just a few minutes of daily practice.
How To Begin Incorporating Tapping Into Your Daily Life
Including tapping in your daily routine can be as simple as taking a few minutes a day to connect with yourself. Upon waking, a brief tapping round can help you set a clear intention and release any tension that arises with the first thoughts of the day. It’s also a useful tool for recognizing how you feel before starting your activities.
During the day, you can turn to tapping in specific moments of discomfort or emotional blockage. If you’re going through a stressful situation, a short pause to apply the technique can help release emotional charge and return to center. Emotions don’t need to be intense—even subtle states like worry or irritation can be addressed effectively.
At night, tapping can help you close the day with greater calm. It’s a good time to review how you felt, give thanks for what you experienced, and let go of what you don’t need to carry into rest. The more natural this space of emotional connection becomes, the easier it will be to return to it whenever you need it.