Study Finds Ayahuasca Affects Epigenetic Gene Expression

Study Finds Ayahuasca Affects Epigenetic Gene Expression

In this Gaia News special investigation, we take a look at groundbreaking new research being done on ayahuasca, an ancient psychedelic plant medicine showing great promise in addressing the most difficult to treat mental health conditions, and may even change our DNA.

Dr. Simon Ruffle is a psychiatrist and researcher who led this study conducted in the Peruvian Amazon.

“Ayahuasca is a psychedelic brew that is used in the Amazon rainforest. It’s been used for at least hundreds of years and there’s some evidence that suggests that it may have been used for thousands of years,” Ruffell said.

“It’s used for a wide variety of purposes and normally by indigenous tribes. It’s used most commonly, now, for healing. And there’s been a lot of interest from people from the West going to the Amazon rainforest in order to drink ayahuasca. And also ayahuasca is spreading all over the world and now can be found on pretty much every continent.”

Watch Part 1:

In part two we look at how researchers found a statistically significant change in the expression of the SIGMAR-1 gene which is thought to be involved with how traumatic memories are recalled.

Watch Part 2:



Ayahuasca Study Shows Breakthrough in Resolving Intercultural Conflict

Can plant medicines heal long-standing, sociopolitical conflicts? A new study brought together groups with deep-rooted enmity for each other in an ayahuasca ceremony—could this be the solution for a more peaceful world?

Plant medicines, including ayahuasca and psilocybin from “magic mushrooms” have become breakthrough therapeutic modalities for treating depression, anxiety, and addiction, as taboos around psychedelics fade and scientists study their effects in sanctioned clinical settings. And now a group of scientists from the US, UK, and Israel has begun to look at ayahuasca as a tool for resolving intercultural conflict. By bringing together Israelis and Palestinians for a group ceremony, the researchers looked for signs of reconciliation and intergroup contact between the subjects.

Dr. Maya Shetreat MD, is a neurologist and herbalist specializing in plant medicine and psychedelic-assisted therapy. She had this to say about the recent study…

“We should definitely be able to experience significant shifts in identity politics because we know that psychedelic medicines like ayahuasca or psilocybin have these ego-dissolving properties that change the way our brains see us, see our identity, and perceive us as being separate from one another,” Dr. Shetreat said. “So, theoretically it’s possible that any kind of identity issues, whether it be political or otherwise, could be more in a place of resolution because people can see past differences.”

Results of this recent study proved to be profound, with several participants reporting visions in which they re-lived trauma from the perspective of those from the opposite culture. And in one instance, a participant was able to embody a single experience from both perspectives. 

But while these results held significant weight for those involved, how does this translate at a larger scale? 

“You know we have to ask the question, is it really necessary for everyone to be in ceremony and go through a psychedelic experience in order to create change? And actually, I think there’s an argument that it doesn’t take that many people, not everybody has to be in that role and enter that liminal space. The people who are called and the people who are motivated to engage with the medicine have those revelations, integrate, take action, and actually lead other people to see those connections that other people might not be able to see,” Dr. Shetreat said.

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