New Gene Discovery May Explain Rapid Human Brain Evolution

New Gene Discovery May Explain Rapid Human Brain Evolution

A revealing new study on human evolution and brain development has just been published. Could this lend credence to the stoned ape theory of brain evolution?

About 300,000-800,000 years ago the human brain experienced a massive and accelerated growth spurt. Scientists have offered many explanations for how and why this may have occurred, but a new study out of Boston Children’s Hospital focused on a fast-evolving set of the human genome called human accelerated regions (HARS). Previous studies have found about 3,100 HARS during brain development, but the team at Children’s Hospital determined one HAR gene PPP1R17 could be responsible for or play a significant role in, rapid brain development. Further, they discovered this works differently in humans than in other animals.

Ben Stewart, the host of Gaia’s Limitless series, said,”[T]hese regions of the human DNA may hold some kind of an answer at the rapid explosion of human neo-cortex because if you think of it evolutionarily, there’s not been one creature, at least on planet Earth, that has been studied that had any organ increase in size as large and as rapidly as the human brain did, so there’s definitely some unanswered questions there.”

“I’m pretty sure that these HARS regions are being looked at for something very unique in the evolution of the brain, and my own personal twist on it is this also might be important when we start looking at brian-machine interfaces and how the brain can potentially cause mutations to adapt to some kind of technology in the brain to enhance or evolve the human brain,” Stewart said.

How could this new discovery be related to the Stoned Ape theory?

“There’s a possibility that the Stoned Ape theory could lead into this. Now, the Stoned Ape theory was really popularized by Terence McKenna,” Stewart said. “Over time, you would have some of our ancient ancestors, hominids, that would be following behind bovine creatures, cows, and in the cow patties in the fields that would naturally, having followed these creatures around for hundreds of thousands of years or whatever it might have been, that they would have started eating the mushrooms, the psilocybin mushrooms that grow naturally in cow patties. These experiences tickling the language centers and other parts of the brain, bringing down the rigidity of the default mode network, and activating other communication hubs within the brain, that could actually explain the rapid explosion of the human neocortex.”

“In this article, they’re saying that these human accelerated regions act differently in humans than they do in primates or creatures like mice and ferrets that they’ve looked into now. So, potentially if there is some connection with the Stoned Ape theory, that psychedelics or psychotropics helped in the expansion of the human neocortex, and made us as, at least psychologically, so much different than the rest of the creatures on Earth, then there may be something to look at here.”



As psychedelic healing and plant medicine go more mainstream, luxury psychedelic tourism is on the rise—good news for the spread of this medicine, but how might over-commercialism affect this sacred practice?

A recent Bloomberg article highlights the rise in all-inclusive psychedelic retreats. Indigenous plant medicine has been around for centuries, and its health benefits have been scientifically demonstrated, but as it gains mainstream acceptance and finds a bigger audience, some only see dollar signs.

Bloomberg reports, “according to Data Bridge Market Research the psychedelic market is expected to grow from $3.8 billion in 2020 to $10.7 billion by 2027.”

With the potential to make a lot of money, could some unscrupulous companies capitalize on this trend and remove the sanctity of this practice?

Carlos Tanner is the director of The Ayahuasca Foundation in Peru, he founded the center in 2009 as the result of his own healing journey. “When I started our retreat center, The Ayahuasca Foundation, I was coming off of a seven-year study myself; a four-year apprenticeship where I lived with a curandero and several years after that of studying with other teachers,” Tanner said.

“For most people that were starting centers at that time—which wasn’t many—you were a student first, and eventually after years of study, you came to the point where you wanted to offer this to people from outside of the culture. Now we see people who don’t have very much experience at all, but yet they’re opening a healing center.”

As this budding industry is dealing with rapid growth, there are some complicated issues regarding its increased popularity.

“When it comes to the commercialization of substances that have an ancestral background I would say that it is a delicate situation, and I hope that there would be a benefit to those indigenous populations from which those traditions were orignated. But at the same time, I know many indigenous people and they are for the spreading of what they believe to be their culture, which oftentimes was something that was looked upon negatively or was degraded as if they were second-class citizens, quite literally,” Tanner said.

“But now having people from the Western world, from the modern world, want to learn or experience elements of their culture, I think gives them a sense of pride. So it’s a complex question, to say the least.”

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