Ketamine Therapy Proves Powerful For Treatment-Resistant Depression

Ketamine Therapy Proves Powerful For Treatment-Resistant Depression

A powerful FDA-approved anesthetic drug once used mainly in operating rooms and on the battlefield is quickly gaining ground as one of the most promising therapies for treatment-resistant mental health conditions.

First discovered as an anesthetic in the 1950s, ketamine has been used in the treatment of a wide range of physical conditions, especially pain management. Starting in the early 1970s, doctors began to find that it can also be very effective in alleviating mental health issues such as depression, anxiety, PTSD, and addiction. Today it is ever more frequently being studied and legally used as an off-label medication to manage conditions that are particularly resistant to treatment with conventional pharmaceuticals.

The latest in a series of recent studies has found that ketamine can quickly and dramatically decrease chronic and suicidal thoughts. Dr. Naveen Thomas is a psychiatrist who has been using ketamine in his practice for years.

“I and many of my colleagues have of course had tremendous success in using ketamine in people who are really suffering from depression. I’ve had a lot of success in treating people with Post-traumatic Stress Disorder,” Dr. Naveen said.

“And some of these folks have spent years and years doing absolutely the best they could using such a wide variety of the conventional treatments, be they various medication treatments, be they various forms of psychotherapy. We’ve seen really wonderful effects.”

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New Studies Find Psychedelics Highly Effective for Alcoholism

New Studies Find Psychedelics Highly Effective for Alcoholism

New studies show unprecedented success in the treatment of alcoholism with psychedelic therapy.

The psychedelic revolution in mental health has produced overwhelming scientific evidence demonstrating the great efficacy of psychedelics in the treatment of various mental health disorders. Now, several new studies involving the drugs ketamine and MDMA are showing significant promise in the treatment of alcoholism.

Dr. Ben Sessa is a psychiatrist and chief medical officer at Awakn Life Sciences, an English biotech company that is at the forefront of the research, development, and delivery of psychedelic medicines.

The company is especially focused on the treatment of Alcohol Use Disorder or AUD, given how prevalent and challenging it is to treat.

“Alcoholism is a huge public health problem. It’s also a psychiatric condition that’s very poorly treated with very poor outcomes with traditional methods,” Sessa said. “Relapse to drinking after getting dry is around 80 to 90 percent at 12 months. That’s an embarrassingly poor statistic. Psychedelics offer a completely new approach; they offer the patient to explore the root causes of addiction, which so often is trauma. Psychedelic-assisted psychotherapy is an intensive upfront piece of work that gets the patient better, so they don’t have to keep coming back. It is a completely different paradigm shift to the way we currently manage patients in maintenance therapies.” 

A recent study conducted by researchers at the University of Exeter and Awakn Life Sciences is the world’s first to examine the use of ketamine to treat AUD in a randomized controlled trial.

“Ketamine is a very well-established human medicine. It is indeed the only psychedelic that’s licensed as a medicine, as an anesthetic medicine, and has been used since the 60s as such. It’s an incredibly safe medicine. When it’s used at a much lower dose, it produces an altered state of consciousness. What we do in psychedelic-assisted psychotherapy with ketamine, is we use this altered state of consciousness to affect a more effective and deeper form of psychotherapy. So, we’re using ketamine as an adjunct to psychotherapy to treat addictions,” he said.  

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