Psychedelics Pioneer Creates Alcohol Substitute With No Toxicity

Psychedelics Pioneer Creates Alcohol Substitute With No Toxicity

In 2009, David Nutt was dismissed from his role as England’s chief drug adviser when he claimed LSD and MDMA were less dangerous than alcohol. Though it’s surely a nuanced argument, Nutt was referring to the relative toxicity between the substances – a fact overshadowed by the cultural stigma surrounding them. And now he’s trying to take that conviction to market with an alcohol substitute called Alcarelle, which gives users the buzz without the horribly toxic side effects.

“The industry knows alcohol is a toxic substance,” said Nutt in an interview with the Guardian. “If it were discovered today, it would be illegal as a foodstuff. The safe limit of alcohol, if you apply food standards criteria, would be one glass of wine a year.”

This hasn’t slowed the consumption of alcohol as the trillion-dollar global industry continues to flourish. Meanwhile, alcohol is attributed to nearly 6 percent of all deaths globally every year – that’s about 3.3 million people killed from alcohol-related issues.

While Nutt’s career is marked by his many breakthroughs studying the psychologically therapeutic effects of psychedelics – and earning him the lengthy title of neuropsychopharmacologist – he’s had his idea for an alcohol alternative on the back burner for decades.

Ever since he began studying alcohol antidotes that reversed the drug’s inebriating effects, Nutt realized that GABA receptors in the brain could be targeted to produce intoxication, while avoiding the elements that damage the liver and other vital organs. And now he believes the market is primed for a release of his product as the extent of alcohol’s adverse effects have become more widely understood.

He also believes the Silicon Valley doctrine of creating “disruptive” technologies has set the stage for his product to infiltrate the behemoth that is the alcohol industry.

In fact, he says he believes the industry will be receptive to his product as major liquor, wine, and beer brands are already investing in alternatives such as cannabis, at the behest of their customers; notably the newer generations that have access to more data and are more health conscientious.

david nutt

David Nutt via independent.co.uk

But instead of trying to convince alcohol producers to revamp their entire process, Nutt says Alcarelle could simply be added to existing product, while the alcohol content is synthesized out or the product not distilled at all.

Nutt has identified the serotonin, dopamine and GABA receptors in the brain that alcohol works across and says he can individually target disparate receptors to achieve desired effects.

Not only could Alcarelle vary in the level of intoxication it induces, but it can also deliver a “capped” drunkenness where, after a certain point, you won’t get any drunker no matter how much you imbibe.

Nutt is currently working on acquiring $26 million in funding to have it properly tested and approved by the appropriate government regulatory agencies, before taking it to market. He already has one investor who provided the seed funding to get the product off the ground.

For now, only a handful of people, mostly he and his colleagues, have had the pleasure of trying his drug, and all are in concurrence that it’s as effective, if not more pleasant than alcohol. If it truly evades liver damage and a hangover, he may have an incredibly desirable compound on his hands. And coming from a man who owns a bar of his own and intends to one day sell Alcarelle at his establishment, it all sounds pretty promising.

 

For more on research conducted in Nutt’s field check out Gaia’s original series Psychedelica:

Psychedelic Society


Cannabis Spirituality: Using Plant Medicine as a Sacred Tool

Cannabis Spirituality: Using Plant Medicine as a Sacred Tool

The stoner stereotype is a familiar one that transcends cultures – lazy, incoherent, silly, and just generally burnt out. But as legalization allows cannabis to be discussed maturely, that trope seems like a dying remnant of the decades-long smear campaign against a plant that can truly impact our lives, culture, and economy in a positive way. With that relaxation of stigma, society can explore a path of cannabis use for spirituality and use it as a tool for inner exploration.

Much like any other psychedelic substance, cannabis can be abused and consumed without respect to its potency, power, or healing potential. There’s virtually no harm in using it as a tool to relax and decompress from life’s daily stresses, but some might argue there’s a point of diminishing return when consuming copious amounts without the right intention.

And for religions that consider the plant sacred, this is typically their view on the use of cannabis — using it heedlessly is considered a sin or frowned upon, while using it for enlightenment or spirituality is accepted, and in some cases, encouraged.

Original Cannabis Spirituality

Cannabis has been used by certain groups as a sacrament for centuries and in some cases maybe even millennia. One of the most notable groups is Rastafarians, who use the plant for meditation and spiritual ceremonies, gathering in a “reasoning” to give praise to Jah (God), who they believe bestowed the herb to man in order to invoke thoughtful insight and self-reflection.

Rastafarians believe cannabis is mentioned in the Bible in Psalm 104:14 where it was written, “He causeth the grass to grow for the cattle and herb for the service of man….”

And in Revelation 22:2 “the herb is the healing of the nations.”

Rastafarianism believes cannabis was used as a sacrament by Moses and the Israelites. Rastas and some Jews believe the plant kaneh bosm, mentioned five times in the Old Testament, was in fact cannabis and an important sacrament for Judaism. Jewish scholars disagree on the translation, but if correct it would imply that the Hebrew Bible was originally blessed with cannabis oil.

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